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Summary of Prospective evaluation of incobotulinumtoxinA in the management of the masseter

Using two different injection techniques

Andreas Nikolis, Kaitlyn M Enright, [...], and Christina Antoniou


(Ref ID:) PMC6047857

Chosen Image filename: PMC6047857_Figure_03.jpg

Document structure and format:

I. Introduction

IncobotulinumtoxinA (Xeomin Cosmetic®) is a popular treatment for managing masseter hypertrophy, but a standardized injection technique is yet to be established. The research paper "Prospective evaluation of incobotulinumtoxinA in the management of the masseter using two different injection techniques" aims to determine the efficacy and safety of these injection techniques. The importance of this study relates to the increasing interest towards non-surgical facial contouring techniques.

II. Methodology

The study used a randomized controlled design to evaluate the effectiveness of two injection techniques, single-injection technique (SIT) and multi-injection technique (MIT), in managing masseter hypertrophy. Thirty female patients with masseteric hypertrophy received incobotulinumtoxinA injection treatments using either the SIT or MIT method. The study assessed the efficacy of the treatments through standardized measurements and photographs, photonumeric scales rated by physicians, and a satisfaction questionnaire completed by patients.

III. Results

The study showed that both the SIT and MIT techniques were effective and safe in managing masseter hypertrophy using incobotulinumtoxinA. No significant differences were observed between the two injection techniques in terms of efficacy and safety. Both patient and physician satisfaction levels were high, with a majority of treated patients being satisfied with the treatment results. The number and severity of adverse events were similar for both groups.

IV. Discussion

The results of the study show that both SIT and MIT techniques using incobotulinumtoxinA are effective and safe in managing masseter hypertrophy. The study indicates that the effectiveness of these techniques is non-inferior to each other. It is suggested that setting a standardized injection technique could prove beneficial for future studies and treatments. However, the sample size of thirty patients and the use of photonumeric scales are limitations of this study, and further research is necessary to assess other injection techniques and their effects on masseter hypertrophy.

V. Conclusion

In summary, the study concludes that both SIT and MIT injection techniques using incobotulinumtoxinA are effective and safe in managing masseter hypertrophy. Standardized injection techniques should be considered for future research, and further investigation should aim to assess additional injection techniques. The results of this study are significant as it contributes to an increased understanding of non-surgical facial contouring techniques.

Figure 3: Overview of the standardized masseter improvement measurements.
Courtesy of PMC6047857


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